|Emmerson Mnangagwa returned to Zimbabwe on Wednesday to a hero's welcome|
The former vice-president - who returned from exile on Wednesday - will be inaugurated at Harare's stadium.
His dismissal this month led the ruling Zanu-PF party and the army to intervene and force Mr. Mugabe to quit.
The opposition is urging Mr. Mnangagwa, who has been part of the ruling elite, to end the "culture of corruption".
The news on Tuesday that 93-year-old Mr. Mugabe was stepping down sparked wild celebrations across the country.
It came in the form of a letter read out in parliament, abruptly halting impeachment proceedings against him.
In it, Mr. Mugabe said he was resigning to allow a smooth and peaceful transfer of power, and that his decision was voluntary.
|President Mugabe was accused of preparing the presidency for his wife Grace|
Neither Mr. Mugabe nor his wife Grace have been seen in public since Sunday, and their whereabouts are unknown.
On Thursday, several reports suggested Mr. Mugabe had been granted immunity from prosecution.
He is not expected to attend Mr. Mnangagwa's inauguration, the BBC's Andrew Harding reports.
The official explanation for Mr. Mugabe's absence is that the 93-year-old needs to rest.
But the fact he is not attending is a stark reminder that this is no ordinary transition, our correspondent adds, that despite his official resignation he was forced out by the military.
The ceremony will be at the 60,000-capacity National Sports Stadium in the capital, with organizers calling on Zimbabweans to come and witness a "historic day".
Ahead of the swearing-in, Mr. Mnangagwa urged Zimbabweans to "remain patient and peaceful and desist from any form of vengeful retribution".
He fled to South Africa two weeks ago - only to return home on Wednesday to a hero's welcome.
|Bank in Zimbabawe|